a hypothesis about lsd

date initiated: 2023 October 22
last updated: 2023 December 7

generalizations from n=1

For some reason, recreational drugs tend to not work as advertised on me.

But I also am able to do things sober that people take drugs for, like stay up late, introspect, feel socially relaxed, etc. When I do take drugs, it’s mostly for the curiosity for how it changes how you think – besides that I find no other upside. This is apparently odd.

I wonder how much is physiological (like hardware, i.e. how many drug-relevant receptors I have) versus psychological (like software i.e. apparently non-stubborn people do better with dementia because they’re more amenable to having their reality corrected).

Alcohol probably skews towards a hardware difference. Alcohol is skewed towards the side effects with little to no fun effects. I suspect I have efficient alcohol to aldehyde (causes the unwanted side effects) conversion, and slow aldehyde to acetic acid (non-toxic end product) conversion; I can get a headache from a shot of beer and can really only get tipsy (which mostly feels like being tired) with liquor/high alcohol percentage. I might as well get sleepy and loopy withh no side effects. [Edit 2023/12/21: I can apparently also get side effects with ‘non-alcoholic alcochol’ (<0.5% alcohol)]

Caffeine I’m not as sure of – it does not seem to help me concentrate/focus better. I drink it for the taste: I like that it’s hot, a strong bitter flavor that is nice to sip slowly as I do work (sweet drinks I tend to down; cold liquids make me distractingly cold and uncomfortable, and hot water is boring). Drinking too much caffeine can make me jittery and unable to sleep though, so it’s similar to alcohol in that its neegative side effects are more salient to me, with little to no observed positive effects.

LSD is commonly advertised to be life-changing, inspirational, etc. As someone generally interested in perspective shifts, I was intrigued. And I guess it was interesting, mostly on a meta-level. I took it with a close friend who also enjoys meta-analyzing things, and our sitter, who has sat others on acid-trips, was baffled that we were still doing it on acid. Apparently it’s not a thing?

I ended taking 1.5x the standard dose because it did not seem to be doing much with one.

Some takes that I have not seen described elsewhere (not that I’ve put much effort to look):

In summary, LSD seems to decrease your resolution of thought, so that a stimulus tends to trigger a longer automated prediction stream. This goes with fewer opportunites for control/decisions, and a regression towards more normal behavior (the possibility space is smaller if there are fewer degrees of freedom).

I’m am not confident this is the best interpretation of my experience, but my friend who likes meta-analyzing said that his experience agreed with my model of it. So, here it is on the internet, in case someone has a similar experience and wants solidarity.

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